Measurement and evaluation of nuclear data of radioisotopes used as tracers are continuously underway in many laboratories to reach high accuracy for their use in production. We briefly mention some of the radionuclides useful for medical diagnostics and other industrial applications. The research group at the Egyptian cyclotron facility (EGCF) performed in collaboration with nuclear research centres and universities in many countries (Germany, Hungary, Finland, USA, Japan and Saudi Arabia) some measurements and evaluations of interesting nuclear reaction data. Nuclear reactions induced by p, d and α-particles on a wide variety of targets were extensively studied from threshold energy up to 50 MeV. Nuclear model code calculations, mainly using EMPIRE and TALYS, were performed for nuclear data validation. Proton and neutron activation of some industrially interesting samples were also studied as technological application of nuclear analytical techniques. Since the cyclotron facility is dedicated to development of the production routes of medical radioisotopes, this overview presents examples of optimization experiments to establish good production conditions.