This paper presents the results of observations of atmospheric and ionospheric parameters performed during a meteorological storm that occurred over the Kaliningrad region in December 2010. The analysis of the observations shows that the ionospheric inhomogeneities at mid-latitudes arising during the periods of meteorological disturbances are manifested as a decrease in the total electron content and the critical frequency of the F2 layer by 33 and 15%, respectively. It is shown that meteorological disturbances of the mid-latitude atmosphere can be manifested in the ionosphere and in the near-equatorial latitudes as increased TEC values. This indicates the complex nature of physical processes that determine the relationship between dynamics in the lower and upper atmosphere.