Based on geomorphologic and digital elevation model (DEM) data, the topographic characteristics of the northwestern edge of the Qinghai-Tibet Plateau are analyzed. Five representative peaks are first determined according to the topographic profile maps for the ridge and piedmont lines, and then the topographic gradient characteristics are analyzed according to the representative topographic profile acquisition method. Based on the geomorphologic database data, the regions between the ridge and the piedmont lines are divided into four geomorphologic zones; and the topographic characteristics are finally analyzed for the different geomorphologic zones regions using the DEM data. The research results show that from the piedmont to the ridge, there exist four geomorphologic zones: arid, fluvial, periglacial and glacial. The arid has the lowest elevation, topographic gradient, relief and slope characteristics. The fluvial has lower elevation and the highest topographic gradient, but with lower relief and slope characteristics. With higher elevation, the periglcial has lower topographic gradient, but the highest relief and slope characteristics. The glacial has the highest elevation with higher topographic gradient, relief and slope characteristics.