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Zeitler, Phil; Hirst, Kathryn; Pyle, Laura; Linder, Barbara; Copeland, Kenneth; Arslanian, Silva; Cuttler, Leona; Nathan, David M; Tollefsen, Sherida; Wilfley, Denise; Kaufman, Francine
New England journal of medicine/The New England journal of medicine, 06/2012, Letnik: 366, Številka: 24Journal Article
In this study of treatments for recent-onset type 2 diabetes, metformin monotherapy was associated with durable glycemic control in about 50% of patients. The addition of rosiglitazone, but not intensive lifestyle intervention, to metformin was superior to metformin alone. Increases in childhood obesity have been accompanied by an increased incidence of type 2 diabetes in youth. 1 , 2 Because the risk of microvascular and macrovascular complications in adults increases with both the duration of diabetes and lack of glycemic control, 3 , 4 it is imperative to achieve and sustain metabolic control in youth. Addressing the physiological and psychological changes that normally occur during adolescence requires a high level of family involvement and makes the achievement of stringent treatment goals especially difficult in the case of adolescents with diabetes. 5 , 6 These challenges are heightened in disadvantaged populations, which are over-represented among adolescents . . .
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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