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Advani, Ranjana; Flinn, Ian; Popplewell, Leslie; Forero, Andres; Bartlett, Nancy L; Ghosh, Nilanjan; Kline, Justin; Roschewski, Mark; LaCasce, Ann; Collins, Graham P; Tran, Thu; Lynn, Judith; Chen, James Y; Volkmer, Jens-Peter; Agoram, Balaji; Huang, Jie; Majeti, Ravindra; Weissman, Irving L; Takimoto, Chris H; Chao, Mark P; Smith, Sonali M
The New England journal of medicine, 11/2018, Letnik: 379, Številka: 18Journal Article
An antibody to CD47 used in combination with rituximab induced responses in half of a small group of patients with refractory B-cell lymphoma. Inhibiting the macrophage checkpoint overcame rituximab resistance by activating macrophage-mediated tumor phagocytosis.
