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Schultz, Nina H; Sørvoll, Ingvild H; Michelsen, Annika E; Munthe, Ludvig A; Lund-Johansen, Fridtjof; Ahlen, Maria T; Wiedmann, Markus; Aamodt, Anne-Hege; Skattør, Thor H; Tjønnfjord, Geir E; Holme, Pål A
The New England journal of medicine, 06/2021, Letnik: 384, Številka: 22Journal Article
This report describes a very rare but life-threatening sequela of vaccination with ChAdOx1 nCoV-19. Within 10 days after a first injection, five health care workers presented with thrombocytopenia and thromboses, including cerebral venous sinus thrombosis with catastrophic outcome. The apparent cause is an anti-PF4 antibody capable of platelet activation; intravenous immune globulin may be therapeutic.
