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Palefsky, Joel M.; Lee, Jeannette Y.; Jay, Naomi; Goldstone, Stephen E.; Darragh, Teresa M.; Dunlevy, Hillary A.; Rosa-Cunha, Isabella; Arons, Abigail; Pugliese, Julia C.; Vena, Don; Sparano, Joseph A.; Wilkin, Timothy J.; Bucher, Gary; Stier, Elizabeth A.; Tirado Gomez, Maribel; Flowers, Lisa; Barroso, Luis F.; Mitsuyasu, Ronald T.; Lensing, Shelly Y.; Logan, Jeffrey; Aboulafia, David M.; Schouten, Jeffrey T.; de la Ossa, Juan; Levine, Rebecca; Korman, Jessica D.; Hagensee, Michael; Atkinson, Thomas M.; Einstein, Mark H.; Cracchiolo, Bernadette M.; Wiley, Dorothy; Ellsworth, Grant B.; Brickman, Cristina; Berry-Lawhorn, J. Michael
The New England journal of medicine, 06/2022, Letnik: 386, Številka: 24Journal Article
Like cervical cancer, anal cancer is often caused by a human papillomavirus and has a premalignant stage called high-grade squamous intraepithelial lesion or anal intraepithelial neoplasia. A randomized trial showed that treating HSIL led to a 57% reduction in progression to anal cancer as compared with active surveillance.
