E-viri
PDF
Recenzirano
Odprti dostop
-
Siccardi, Marco; D'Avolio, Antonio; Baietto, Lorena; Gibbons, Sara; Sciandra, Mauro; Colucci, Daniela; Bonora, Stefano; Khoo, Saye; Back, David J.; Perri, Giovanni Di; Owen, Andrew
Clinical infectious diseases, 11/2008, Letnik: 47, Številka: 9Journal Article
This study investigated pregnane X receptor polymorphisms in relation to unboosted atazanavir plasma concentrations in 2 cohorts of patients. The polymorphism 63396T→C predicted concentrations below the minimum effective concentration (150 ng/mL) with odds ratios of 18 (P=.008) and 5.13 (P=.02). Prospective studies determining potential clinical usefulness are now warranted.
