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Fujita, Shohei; Gagoski, Borjan; Hwang, Ken-Pin; Hagiwara, Akifumi; Warntjes, Marcel; Fukunaga, Issei; Uchida, Wataru; Saito, Yuya; Sekine, Towa; Tachibana, Rina; Muroi, Tomoya; Akatsu, Toshiya; Kasahara, Akihiro; Sato, Ryo; Ueyama, Tsuyoshi; Andica, Christina; Kamagata, Koji; Amemiya, Shiori; Takao, Hidemasa; Hoshino, Yasunobu; Tomizawa, Yuji; Yokoyama, Kazumasa; Bilgic, Berkin; Hattori, Nobutaka; Abe, Osamu; Aoki, Shigeki
Magnetic resonance in medicine, 05/2024, Letnik: 91, Številka: 5Journal Article
To evaluate a vendor-agnostic multiparametric mapping scheme based on 3D quantification using an interleaved Look-Locker acquisition sequence with a T2 preparation pulse (3D-QALAS) for whole-brain T1, T2, and proton density (PD) mapping. This prospective, multi-institutional study was conducted between September 2021 and February 2022 using five different 3T systems from four prominent MRI vendors. The accuracy of this technique was evaluated using a standardized MRI system phantom. Intra-scanner repeatability and inter-vendor reproducibility of T1, T2, and PD values were evaluated in 10 healthy volunteers (6 men; mean age ± SD, 28.0 ± 5.6 y) who underwent scan-rescan sessions on each scanner (total scans = 100). To evaluate the feasibility of 3D-QALAS, nine patients with multiple sclerosis (nine women; mean age ± SD, 48.2 ± 11.5 y) underwent imaging examination on two 3T MRI systems from different manufacturers. Quantitative maps obtained with 3D-QALAS showed high linearity (R = 0.998 and 0.998 for T1 and T2, respectively) with respect to reference measurements. The mean intra-scanner coefficients of variation for each scanner and structure ranged from 0.4% to 2.6%. The mean structure-wise test-retest repeatabilities were 1.6%, 1.1%, and 0.7% for T1, T2, and PD, respectively. Overall, high inter-vendor reproducibility was observed for all parameter maps and all structure measurements, including white matter lesions in patients with multiple sclerosis. The vendor-agnostic multiparametric mapping technique 3D-QALAS provided reproducible measurements of T1, T2, and PD for human tissues within a typical physiological range using 3T scanners from four different MRI manufacturers.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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