Sauroine, an Alkaloid from Huperzia saururus with Activity in Wistar Rats in Electrophysiological and Behavioral Assays Related to Memory Retention

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Sauroine, an Alkaloid from Huperzia saururus with Activity in Wistar Rats in Electrophysiological and Behavioral Assays Related to Memory Retention

Vallejo, Mariana G; Ortega, María G; Cabrera, José L; Carlini, Valeria P; Rubiales de Barioglio, Susana; Almirón, Romina S; Ramírez, Oscar A; Agnese, A. Mariel

Journal of natural products, 01/2009, Letnik: 72, Številka: 1

Journal Article

The present study describes the effects of sauroine (1), the main alkaloid obtained from Huperzia saururus, on memory retention and learning. To evaluate this, electrophysiological experiments and behavioral tests (step down) were performed on male Wistar rats. The results showed that 1 improved memory retention in the step-down test, significantly increasing hippocampal plasticity. Thus, 1 seems to be a constituent responsible for the activity claimed in folk medicine for H. saururus in Argentina.

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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.

Leto	Faktor vpliva		Izdaja		Kategorija		Razvrstitev
Leto	JCR	SNIP	JCR	SNIP	JCR	SNIP	JCR	SNIP

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