The purpose of this meta-analysis is to explore the relationship between family-of-origin factors (i.e., attachment, witnessing inter-parental violence, experiencing abuse as a child, poor parenting, and parental support) and physical teen dating violence (TDV i.e., physical acts, such as hitting, kicking, or using force to hurt another person) victimization and perpetration. We included a total of 27 studies, which yielded 81 effect sizes examining physical TDV perpetration and victimization, in this study. We found that anxious attachment was the strongest risk marker for physical TDV perpetration and experiencing abuse as a child was the strongest risk marker for physical TDV victimization. Our results also revealed that witnessing inter-parental violence was a significant risk marker for physical TDV perpetration and victimization, poor parenting was a significant risk marker for physical TDV victimization, avoidant attachment and experiencing abuse as a child were significant risk markers for perpetration, and parental support was a significant protective marker against physical TDV victimization. Our findings highlight the importance of family factors when identifying adolescents who are at risk for physical TDV, particularly those who have experienced abuse as a child and have an insecure attachment. They can also be used by parent educators to inform parenting practices and encourage parents to model healthy relationships for their children. Highlights This meta-analysis examines the relationship between family-of-origin factors and physical teen dating violence (TDV). Anxious attachment was the strongest risk marker for TDV perpetration, followed by witnessing inter-parental violence, experiencing child abuse, and avoidant attachment. Experiencing abuse as a child was the strongest risk marker for TDV victimization, followed by witnessing inter-parental violence and poor parenting. Parental support was a significant protective marker against physical TDV victimization.