Carpal tunnel syndrome (CTS) is a widely distributed upper limb nerve compression. CTS is relatively easy to recognise with timely diagnosis of symptoms. The elimination of risks and professional conservative therapy can prevent the radical interventions. In our study we worked with 8 patients, 7 of them had signs of CTS in both hands. The diagnosis was based on history, physical examinations and an electroneurographia test (ENG). All of the patients completed a questionnaire about their subjective symptoms before the objective physical examinations. The used physiotherapy was modified for the severity of the symptoms. Advice on workplace task modification was given to all patients. Main symptoms are tingling, numbness, nocturnal pain and weakness in the distribution of the median nerve in the hand. Objective results represented a decrease in the range of motion, waste of force in the hand and thenar atrophy. After the treatment the waste of the abductor pollicis has disappeared in all patients, weakness and deficits of motion were found in one person. We recognised a significant improvement in the specific tests. Occupational factors, overstrain of the hands are important causes of CTS. Loss of sensory feedback and pain is more often presented than motor function loss. After the treatment the symptoms of patients were reduced or disappeared. CTS can be often effectively treated with complex physiotherapy and workplace task modifications, but there isn’t a complete recovery in all cases.