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Hernanz, Nerea; Rodríguez de Santiago, Enrique; Marcos Prieto, Héctor Miguel; Jorge Turrión, Miguel Ángel; Barreiro Alonso, Eva; Rodríguez Escaja, Carlos; Jiménez Jurado, Andrea; Sierra, María; Pérez Valle, Isabel; Volpato, Nadja; García Prada, María; Nuñez-Gómez, Laura; Ríos-León, Raquel; Castaño García, Andrés; García de Paredes, Ana García; Aicart, Marta; Caminoa, Alejandra; Peñas Parcía, Beatriz; Vázquez-Sequeiros, Enrique; Albillos, Agustín
Digestive and liver disease, June 2019, 2019-06-00, 20190601, Letnik: 51, Številka: 6Journal Article
Missed gastric cancer (MGC) is poorly documented in Mediterranean populations. (1) To assess the rate, predictors and survival of MGC. (2) To compare MGC and non-MGC tumors. This is a retrospective-cohort study conducted at four centers. MGC was defined as cancer detected within three years after negative esophagogastroduodenoscopy. Gastric adenocarcinomas diagnosed between 2008–2015 were included. Patients with no follow-up were excluded. During the study period 123,395 esophagogastroduodenoscopies were performed, with 1374 gastric cancers being diagnosed (1.1%). A total of 1289 gastric cancers were finally included. The overall rate of MGC was 4.7% (61/1289, 3.7–6%). A negative esophagogastroduodenoscopy in MGC patients was independently associated with PPI therapy (p < 0.001), previous Billroth II anastomosis (p = 0.002), and lack of alarm symptoms (p < 0.001). The most frequent location for MGC was the gastric body(52.4%). MGCs were smaller than non-MGCs (31 vs 41 mm, p = 0.047), more often flat or depressed (p = 0.003) and less likely to be encountered as advanced disease. Overall 2-year survival was similar between MGC (34.1%) and Non-MGC (35.3 %) (p = 0.59). MGC accounted for nearly five percent of newly-diagnosed gastric adenocarcinomas. Overall survival was poor and not different between MGC and non-MGC.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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