E-viri
Recenzirano
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Matsumoto, Takahiro; Kitagawa, Takahiro; Ohta, Tomoe; Yoshida, Tatsusada; Imahori, Daisuke; Teo, Stephen; Ahmad, Haji Sapuan bin; Watanabe, Tetsushi
Journal of natural medicines, 09/2019, Letnik: 73, Številka: 4Journal Article
From the methanolic extract of the leaves of Lansium domesticum , three new onoceranoid-type triterpenoids, lansium acids X–XII and a new cycloartane-type triterpene, lansium acid XIII, were isolated. The chemical structures of the isolated new compounds were elucidated on the basis of chemical/physicochemical evidence. For new onoceranoid-type triterpenoids, the absolute configurations were established by comparison of experimental and predicted electronic circular dichroism (ECD) data. The isolated onoceranoid-type triterpenoids showed antimutagenic effects in the Ames assay against 3-amino-1,4-dimethyl-5 H -pyrido4,3- b indole (Trp-P-1).
