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  • Pan-drug resistant Providen...
    Mc Gann, Patrick; Geringer, Matthew R.; Hall, Lindsey R.; Lebreton, Francois; Markelz, Elizabeth; Kwak, Yoon I.; Johnson, Sheila; Ong, Ana C.; Powell, Aubrey; Tekle, Tsigereda; Bergman, Yehudit; Simner, Patricia J.; Bennett, Jason W.; Cybulski, Robert J.; White, Brian K.

    Journal of Medical Microbiology/Journal of medical microbiology, 08/2021, Letnik: 70, Številka: 8
    Journal Article

    Following prolonged hospitalization that included broad-spectrum antibiotic exposure, a strain of Providencia rettgeri was cultured from the blood of a patient undergoing extracorporeal membrane oxygenation treatment for hypoxic respiratory failure due to COVID-19. The strain was resistant to all antimicrobials tested including the novel siderophore cephalosporin, cefiderocol. Whole genome sequencing detected ten antimicrobial resistance genes, including the metallo-β-lactamase bla NDM-1 , the extended-spectrum β-lactamase bla PER-1 , and the rare 16S methyltransferase rmtB2 .