New experimental measurements for 16 O +  12 C elastic scattering angular distribution at E lab  = 27 MeV were performed at the cyclotron DC-60 INP RK. The measured data as well as the previous measurements for 16 O +  12 C angular distributions in the energy range E lab  = 20–140 MeV are subjected to detailed analysis using the double folding optical potential. For this purpose, different models of interaction potentials are used, such as the BDM3Y1-Reid and the CDM3Y1-Paris based on the M3Y interactions. The new B3Y-Fetal potentials are also tested, and the efficiency of the DDB3Y1-Fetal interaction to increase the saturation properties of cold nuclear matter was studied in comparison with the well-known BDM3Y1-Reid and CDM3Y1-Paris interactions.