Objectives . To establish the developmental features, family history, social adaptation, and structure of early psychopathological disorders in pediatric patients with schizotypal disorder (STD) and their relationship with the manifestation and clinical structure of the disease. Materials and methods. The study included 150 patients aged 7–16 years with a diagnosis of STD, of whom 48 were female and 102 were male. Five groups of patients were identified on the basis of the age of onset of the first stable psychopathological disorders prior to diagnosis of STD: up to three years ( n = 38), 4–6 years ( n = 36), 7–10 years ( n = 15), 11–13 years ( n = 41) and 14–16 years ( n = 20). Clinical-psychopathological, clinical-historical, neurological, pathopsychological, psychometric, and statistical investigation methods were used. Results. A high frequency of deviations from normal values of indicators in early psychomotor development was found (in 99 patients, 65%). Delayed mental development was observed in 23 patients (15%) and dissociation in mental development – in 62 patients (41%). Impairments were significantly more frequent in groups with onset of psychopathological disorders at age up to six years; simultaneous impairments in three domains – emotional, motivational and volitional were more common (38%) than in the fourth group (13%). Groups 1 and 2 showed deficit in intellectual development. High performance in the primary grades was observed in 16% of patients in group 1 vs. 60% in group 5. The diagnosis of schizotypal personality disorder was significantly more commonly (66%) diagnosed in patients of group 1, while the psychopathic variant of STD was diagnosed at age 7 to 13 years and the neurosis-like variant had a clear tendency to become more frequent with increasing age. Conclusions. The age of onset and the duration of the persistence of psychopathological disorders determine the level of negative changes formed at the stage of disease preceding onset of distinct clinical symptoms of STD, while age at the time of manifestation of disease affects the predominant positive disorders.