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Bhatia, Shobna J.; Makharia, Govind K.; Abraham, Philip; Bhat, Naresh; Kumar, Ajay; Reddy, D. Nageshwar; Ghoshal, Uday C.; Ahuja, Vineet; Rao, G. Venkat; Devadas, Krishnadas; Dutta, Amit K.; Jain, Abhinav; Kedia, Saurabh; Dama, Rohit; Kalapala, Rakesh; Alvares, Jose Filipe; Dadhich, Sunil; Dixit, Vinod Kumar; Goenka, Mahesh Kumar; Goswami, B. D.; Issar, Sanjeev K.; Leelakrishnan, Venkatakrishnan; Mallath, Mohandas K.; Mathew, Philip; Mathew, Praveen; Nandwani, Subhashchandra; Pai, Cannanore Ganesh; Peter, Lorance; Prasad, A. V. Siva; Singh, Devinder; Sodhi, Jaswinder Singh; Sud, Randhir; Venkataraman, Jayanthi; Midha, Vandana; Bapaye, Amol; Dutta, Usha; Jain, Ajay K.; Kochhar, Rakesh; Puri, Amarender S.; Singh, Shivram Prasad; Shimpi, Lalit; Sood, Ajit; Wadhwa, Rajkumar T.
Indian journal of gastroenterology, 10/2019, Letnik: 38, Številka: 5Journal Article
The Indian Society of Gastroenterology developed this evidence-based practice guideline for management of gastroesophageal reflux disease (GERD) in adults. A modified Delphi process was used to develop this consensus containing 58 statements, which were generated by electronic voting iteration as well as face-to-face meeting and review of the supporting literature primarily from India. These statements include 10 on epidemiology, 8 on clinical presentation, 10 on investigations, 23 on treatment (including medical, endoscopic, and surgical modalities), and 7 on complications of GERD. When the proportion of those who voted either to accept completely or with minor reservation was 80% or higher, the statement was regarded as accepted. The prevalence of GERD in India ranges from 7.6% to 30%, being < 10% in most population studies, and higher in cohort studies. The dietary factors associated with GERD include use of spices and non-vegetarian food. Helicobacter pylori is thought to have a negative relation with GERD; H. pylori negative patients have higher grade of symptoms of GERD and esophagitis. Less than 10% of GERD patients in India have erosive esophagitis. In patients with occasional or mild symptoms, antacids and histamine H 2 receptor blockers (H2RAs) may be used, and proton pump inhibitors (PPI) should be used in patients with frequent or severe symptoms. Prokinetics have limited proven role in management of GERD.
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