Nanotechnology has underpinned vital progress in current research and has immensely promoted the food production chain. This review projected the critical intervention of nano-based technologies like modern advancements of nano-based biosensors in detecting mycotoxins, microbial contaminations, antibiotics, pesticides, food additives, and dyes. It also highlighted the starring roles of nanotechnology in terms of active, intelligent food packaging and food safety. These approaches have certainly intensified the strength of food processing technology and improved food quality and maintenance standards during shelf life. Apart from these trending facets, this review throw light on the utilisation of food waste for the biogenic synthesis of nanoparticles and the application of nano-based materials for the recycling process in food production units to ensure a complete cleaner technology. However, monitoring the chronic exposure of food contact nanomaterials should be critically evaluated to ensure food safety. Nanotechnology embraced an influential role in the food sector by providing effective avenues for energy conservation, sustainability, and cues to improve the capital funds well. Display omitted •Role of nano-biosensors for detection of toxic residues in food.•Naturally occurring nano-foods as models to understand the penetrable properties.•Utilisation of food waste for energy sustainability through eco-waste management.•Nanomaterials in recycling units of food factories ensure cleaner production.•Improved bioavailability of nutrients and food safety through active packaging.