Introduction: Bruxism is an occlusal parafunction that is globally quite common. Early diagnosis would lead to early therapy and hence early prevention from damage to the stomatognathic system caused by this parafunctional. Aim: Demonstration of using individually designed dentures - night dentures in a patient with a condition of partial edentulousness with diagnosed bruxism. A case study: In a patient aged 63 with painful symptomatology, we performed extraoral and intraoral clinical examination. An individually designed denture - night denture was constructed of two types of material before and after the prosthetic rehabilitation. Results and Discussion: After making the fixed-mobile construction, the teeth and the periodontal complex were protected. After wearing the individually designed dentures, the patient felt a reduction of pain deriving from the masticatory muscles and the temporomandibular joint. The materials for creating these dentures allow their easy production and application in clinical practice. Conclusion: The success was achieved in preserving the prosthetic construction and improving the health of the stomatognathic system of the patient, thus achieving the goal of justifying the use of this new type of designed denture.