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Wei, Lai; Chiu, David Kung-Chun; Tsang, Felice Ho-Ching; Law, Dicky Cheuk-Ting; Cheng, Carol Lai-Hung; Au, Sandy Leung-Kuen; Lee, Joyce Man-Fong; Wong, Carmen Chak-Lui; Ng, Irene Oi-Lin; Wong, Chun-Ming
Journal of hepatology, 10/2017, Letnik: 67, Številka: 4Journal Article
Graphical abstract Deregulation of G9a in human HCC. G9a was frequently up-regulated in human HCC and implicated in HCC tumorigenesis and metastasis. The frequent up-regulation of G9a in human HCC was attributed to gene copy number gain at 6p21 and loss of miR-1. The oncogenic function of G9a was at least partially attributed to the epigenetic silencing of tumor suppressor RARRES3.
