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Rolfs, Robert T; Joesoef, M. Riduan; Hendershot, Edward F; Rompalo, Anne M; Augenbraun, Michael H; Chiu, Michael; Bolan, Gail; Johnson, Steven C; French, Pamela; Steen, Eric; Radolf, Justin D; Larsen, Sandra; Brady, William E; Wagner, Kenneth F; D'Aquilante, Debra A
The New England journal of medicine, 07/1997, Letnik: 337, Številka: 5Journal Article
Since 1987, several reports have described neurosyphilis and other complications of syphilis in patients infected with the human immunodeficiency virus (HIV), 1 – 7 often after the patients have been treated with penicillin G benzathine, as recommended by the Centers for Disease Control and Prevention (CDC). Also, in 1987 viable treponemes were identified in the cerebrospinal fluid of two HIV-infected patients after this therapy. 8 These observations have prompted questions about the adequacy of the CDC-recommended treatment for HIV-infected patients with early syphilis. 3 , 9 – 11 The efficacy of the recommended therapy for patients with early syphilis who are not infected with HIV was . . .
