E-viri
Recenzirano
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Uygun, Vedat; Özsan, Nazan; Daloğlu, Hayriye; Öztürkmen, Seda; Yalçın, Koray; Karasu, Gülsün; Yeşilipek, Akif
International journal of hematology, 04/2022, Letnik: 115, Številka: 4Journal Article
EBV-associated lymphoproliferative disorders (LPDs) are common in hematopoietic stem cell transplantation (HSCT) with T-cell-depleted grafts, but are extremely rare in HSCT patients with T-cell-replete grafts with post-transplant cyclophosphamide (PTCy). Here we present the cases of two pediatric patients who developed EBV-related LPD after T-cell-replete haplo-HSCT with PTCy. One of these is the first reported case of EBV-positive mucocutaneous ulcer (EBVMCU) developing after PTCy. EBV-related diseases are rare in T-cell-replete haplo-HSCT patients with PTCy. However, in patients with risk factors, it is reasonable to screen for EBV viremia for LPD.
