E-viri
Recenzirano
-
Baldermann, Juan Carlos; Schüller, Thomas; Huys, Daniel; Becker, Ingrid; Timmermann, Lars; Jessen, Frank; Visser-Vandewalle, Veerle; Kuhn, Jens
Brain stimulation, 03/2016, Letnik: 9, Številka: 2Journal Article
Highlights • We conducted the first meta-analysis and a systematic review on clinical effects of deep brain stimulation in Tourette syndrome. • A significant median reduction of 53% in the Yale Global Tic Severity Scale was observed. • Comorbid depressive and obsessive-compulsive symptoms significantly improved. • Different brain targets showed comparable improvement rates, indicating a modulation of a common network. • Overall, younger patients may profit more from deep brain stimulation but different targets also provide different predictive values.
