Natural and anthropogenic factors in coastal wetland changes are widely discussed in wetland studies. Previous literatures have demonstrated that many factors may cause wetland change and argued that the global climate change and nutrient enrichment may become the most important ones in the next 50 years. Through field investigation, with the help of remote sensing technology and geographic information system, this research discusses the wetland change in Tianjin under the great pressure of rapid economic development, population growth, and sea-level rising. These findings include: (1) the wetland area expanded from 466.50 km 2 to 658.38 km 2 between 1987 and 1998, but it shrank to 550.5 km 2 by the year of 2006. (2) The results show that the groundwater has not been contaminated while the surface water has been polluted. (3) The questionnaire survey shows that the social environment in some specific ways impedes the protection of natural reserve. In order to achieve the harmony between human and nature, feasible countermeasures on how to keep ecological balance should be immediately taken. Consequently, natural conservation and sustainable economic development will be realized.