The Ambaji–Deri region is located in the northeastern part of the Gujarat state of India and is well-known for hosting lead–zinc–copper minerals deposits. Recently, gravity and magnetic data are collected in the region with the objective of geological and structural mapping of the area. This data is further processed using upward continuation, derivative analysis, and 2.5-dimensional gravity modelling to understand the subsurface geometry for mineral exploration. The upward continued regional gravity anomaly reveals high value in SW part of the region. The residual gravity and magnetic anomaly show the NE–SW trend, which is sympathetic with the general trend of Delhi supergroup. The high values of the residual Bouguer and the magnetic anomaly at the junction of the Jaisalmer–Barwani and the Chambal–Jamnagar lineaments are inferred as possible potential sites for sulphide mineralisation. The horizontal gradient of the tilt derivative (HGTD) of both the gravity and the magnetic anomalies reveals NE–SW trending lineaments. Based on the results of HGTD, several new structural features have been identified and a refined lineament map of the study area is proposed. The gravity modelling using residual Bouguer anomaly could delineate a high-density intrusive body in the upper crustal level. The result of the gravity model also confirms that the middle crust is uplifted by 1–3 km in the eastern part of the study area. In this study, three prospective zones for base metal mineralisation have been identified.