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Bosma, Piter J; Chowdhury, Jayanta Roy; Chowdhury, Namita Roy; Bakker, Conny; Gantla, Shailaja; de Boer, Anita; Oostra, Ben A; Lindhout, Dick; Tytgat, Guido N.J; Jansen, Peter L.M; Elferink, Ronald P.J. Oude
New England journal of medicine/The New England journal of medicine, 11/1995, Letnik: 333, Številka: 18Journal Article
People with Gilbert's syndrome have mild, chronic unconjugated hyperbilirubinemia in the absence of liver disease or overt hemolysis. 1 , 2 Although the syndrome is inherited, many people do not have a clear family history. 3 An autosomal mode of inheritance has been proposed, 4 and more recently, a recessive pattern of inheritance has been suggested. 5 On the basis of serum bilirubin levels, 3 to 10 percent of the general population are estimated to have Gilbert's syndrome. 6 – 8 Serum bilirubin levels fluctuate in people with Gilbert's syndrome and often fall within accepted normal limits, making it unclear whether these people constitute a distinct subpopulation . . .
