E-viri
Recenzirano
Odprti dostop
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De Miguel Buckley, Rosa; Rial-Crestelo, David; Montejano, Rocío; Pinto, Adriana; Jimenez-Gonzalez, María; Lagarde, Maria; Esteban-Cantos, Andrés; Aranguren-Rivas, Paula; Cadiñanos, Julen; Bisbal, Otilia; Castro, Juan Miguel; Santacreu-Guerrero, Mireia; Bermejo-Plaza, Laura; Moreno, Victoria; Hernando, Asunción; Martín-Carbonero, Luz; Rubio, Rafael; Delgado, Rafael; Arribas, José Ramón; Pulido, Federico
Open forum infectious diseases, 11/2022, Letnik: 9, Številka: 11Journal Article
Abstract In this pilot clinical trial, we evaluated rates of residual replication in persons without lamivudine resistance-associated mutations in proviral DNA population sequencing who switched to dolutegravir plus lamivudine. After 144 weeks, there was no signal of changes in residual viremia based on qualitative detection methods, irrespective of past lamivudine resistance. Clinical Trials Registration. NCT03539224.
