Characteristics, Management, and Outcomes of 5,557 Patients Age ≥90 With Acute Coronary Syndromes: Results From the CRUSADE Initiative Adam H. Skolnick, Karen P. Alexander, Anita Y. Chen, Matthew T. Roe, Charles V. Pollack, Jr, E. Magnus Ohman, John S. Rumsfeld, W. Brian Gibler, Eric D. Peterson, David J. Cohen We examined baseline characteristics, treatment patterns, and in-hospital outcomes among 5,557 patients with non–ST-segment elevation acute coronary syndromes entered into the CRUSADE registry age ≥90 years compared with a younger elderly cohort age 75 to 89 years. The older elderly were similar to the younger group in many respects but had lower rates of smoking, diabetes, or obesity and were less likely to receive heparin, glycoprotein IIb/IIIa inhibitors, or statins. They were more likely to die or experience any adverse event. Among both groups, increasing adherence to guideline-recommended therapies was associated with both increased bleeding and lower risk-adjusted in-hospital mortality.