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  • Comparative Preclinical Pha...
    Kolyvanov, G. B.; Zherdev, V. P.; Gribakina, O. G.; Bochkov, P. O.; Shevchenko, R. V.; Litvin, A. A.; Blynskaya, E. V.; Bueva, V. V.

    Bulletin of experimental biology and medicine, 09/2019, Letnik: 167, Številka: 5
    Journal Article

    Pharmacokinetics and relative bioavailability of antidepressant GSB-106 (hexamethylendiamide bis -( N -monosuccinyl- L -seryl- L -lysine) were determined in rabbits after single oral administration of the pharmaceutical substance and tablet mass. GSB-106 concentrations in the blood plasma were determined by HPLC-mass spectrometry. Relative bioavailability of GSB-106 tablet form was 160.79±24.33%.