Direction-of-arrival (DOA) estimation is the preliminary stage of communication, localization, and sensing. Hence, it is a canonical task for next-generation wireless communications, namely beyond 5G (B5G) or 6G communication networks. Both massive multiple-input multiple-output (MIMO) and millimeter wave (mmW) bands are emerging technologies that can be implemented to increase the spectral efficiency of an area, and a number of expectations have been placed on them for future-generation wireless communications. Meanwhile, they also create new challenges for DOA estimation, for instance, through extremely large-scale array data, the coexistence of far-field and near-field sources, mutual coupling effects, and complicated spatial-temporal signal sampling. This article discusses various open issues related to DOA estimation for B5G/6G communication networks. Moreover, some insights on current advances, including arrays, models, sampling, and algorithms, are provided. Finally, directions for future work on the development of DOA estimation are addressed.