In order to solve connectivity problems in metropolitan areas, the development of underground metro lines constitutes an unquestionable requirement. However, the construction work thereof encounters unfavourable circumstances when surface excavations must be carried out that cross historical areas of the city, due to the need to control surface movements. The design of the metro in the city of Seville (Spain) from 2004 to 2006 provides a representative example of this situation and triggered major upheavals that exerted repercussions on historical buildings. For these reasons, the excavation stages of Line 1 of this metro have been simulated by numerical methods using FLAC3D software and validated with the results provided by the real conditions. Consequently, various surface settlements have been evaluated by taking not only variates of the main parameters that characterise the soil of Seville, but also of the various load situations and excavation conditions. Notable results have been achieved through calibration of 54 variants of the same model corresponding to Line 1, and their comparison with the real results obtained in nine critical areas of the itinerary. The results obtained have made it possible to determine the effects of excavation on the subsoil of the city of Seville with great accuracy, since the percentage error of calculated vertical surface movements varies from 0.1% to 5.3%.