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Samalova, Marketa; Flamant, Patricia; Beau, Rémi; Bromley, Mike; Moya-Nilges, Maryse; Fontaine, Thierry; Latgé, Jean-Paul; Mouyna, Isabelle
Journal of Fungi, 02/2023, Letnik: 9, Številka: 2Journal Article
GPI-anchored proteins display very diverse biological (biochemical and immunological) functions. An in silico analysis has revealed that the genome of contains 86 genes coding for putative GPI-anchored proteins (GPI-APs). Past research has demonstrated the involvement of GPI-APs in cell wall remodeling, virulence, and adhesion. We analyzed a new GPI-anchored protein called SwgA. We showed that this protein is mainly present in the of and is absent from yeasts and other molds. The protein, localized in the membrane of , is involved in germination, growth, and morphogenesis, and is associated with nitrogen metabolism and thermosensitivity. is controlled by the nitrogen regulator AreA. This current study indicates that GPI-APs have more general functions in fungal metabolism than cell wall biosynthesis.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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