The article addresses the peculiarities of German semantic loans in Ukrainian local dialects of Zakarpattia and their influence on the lexical-semantic system of the latter considering inter-language relations, particularly, semantic interference of languages. The conducted research suggests that this impact leads to internal and structural transformations in a lexical-semantic group or semantic field where particular Ukrainian vernaculars of Zakarpattia belong. The analysis focuses on the significance of these transformations since they concern the word form as well as the meaning and word combinability. The authors aim to explore the distinctive structural-semantic features of German loanwords in Ukrainian vernaculars of Zakarpattia.