Background: In Japan, the number of pediatric cancer cases was approximately 2,200 in 2019. Notably, 15 hospitals are designated for pediatric cancer in Japan. This study focused on the outpatient nurses of a pediatric specialty hospital supporting these designated hospitals. The study aimed to clarify the support that these nurses provide to pediatric cancer survivors as well as their thoughts on supporting the patients at pediatric specialty hospitals. Methods: This study used qualitative inductive research methods and conducted semi-structmed free-response interviews with outpatient nurses working at a pediatric specialty hospital. Data analysis was performed using the Modified Grounded Theory Approach (M-GTA). Results: Overall, 15 outpatient nurses were included in the study. Moreover, the M-GTA analysis generated four core categories. The thought process related to a long-term follow-up outpatient clinic for pediatric cancer survivors included considering factors that posed difficulty in the establishment of such a clinic, reconsidering the importance of establishing such a clinic, and contemplating about establishing a desirable clinic. This was based on the belief of the outpatient nurses regarding building a trusting relationship with the patients. Conclusion: Owing to manpower issues, no guidance was provided for the pediatric cancer survivors at outpatient clinics, and follow-up care was provided only by physicians. Moreover, outpatient nurses recognized the problems faced by patients throughout their lives and understood the need to solve them, but they could not provide effective guidance. Because pediatric cancer survivors are at high risk of disease- and treatment-related outcomes, there is a need to develop a system that facilitates collaboration between different professional groups in order to improve their quality of life.