For years, the building sector has been marked by the progressive exploitation of raw materials and the growing production of waste. The product and process innovations, based on waste valorisation starting from their geographical location and identification, prefigure potential reductions of environmental impacts. This paper presents the methodology and findings of the mapping of waste from construction and manufacturing processes, carried out in Sardinia to identify possible scenarios of valorisation. The geographical location of waste production both in construction and manufacturing processes, along with their possible reuse, have allowed the definition of some supply chains which are able to process their own waste, according to industrial symbiosis scenarios.