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Kriegelstein, Michal; Nováková, Gabriela; Marek, Aleš
Journal of labelled compounds & radiopharmaceuticals 67, Številka: 3Journal Article
The synthesis of tritium-labelled glycine transporter 1 inhibitor Org24598 is reported. Because of the instability of the Org24598 skeleton under hydrogenation conditions, a synthetic approach using an in-house prepared tritium-labelled alkylating agent ( HMeI, SA = 26.2 Ci/mmol) was employed. Alternative methods of labelling are discussed.
![Synthesis of [ 3 H]Org24598...](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/0362-4803/medium "Synthesis of [ 3 H]Org24598 using in-house prepared [ 3 H]MeI")
