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Weng, Wei-Zhi; Xie, Jian; Zhang, Bo
Organic & biomolecular chemistry, 06/2018, Letnik: 16, Številka: 21Journal Article
A simple and efficient approach for the preparation of substituted indoles and isoquinolones via a nickel-catalyzed Larock-type heteroannulation reaction is reported. This transformation employed air-stable and inexpensive Ni(dppp)Cl as a precatalyst and Et N as a mild base. Moreover, the reaction occurs efficiently under mild conditions, and a wide range of substituted indoles and isoquinolones bearing various functional groups are obtained in moderate to excellent yields.
