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  • A new flavonoid from the le...
    Nguyen, Thi Thu Ha; Nguyen, Van Tuyen; Van Cuong, Pham; Nguyen Thanh, Tra; Le Thi, Tu Anh; Mai Huong, Doan Thi; Truong, Bich Ngan; Litaudon, Marc; Ninh The, Son

    Natural product research, 10/2022, Letnik: 36, Številka: 19
    Journal Article

    From the ethyl acetate extract (EtOAc) of the Vietnamese leaves, a new flavone 8- -glycoside 2'',6''-di- -acetylvitexin ( ), together with six known analogs were isolated. Their structures were determined by spectral methods and compared with literature data. In α-glucosidase inhibitory assay, the EtOAc extract and its flavone and biflavone derivatives possessed the significant IC range of 9.17-97.53 µM, as compared with that of the positive control acarbose (249 µM). Flavones and biflavones showed are better than flavone glycosides in both α-glucosidase and acetylcholinesterase inhibitory activities.