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  • Evaluating Fourier-transfor...
    Nakajima, Naoki; Jinnai, Michio; Izumiyama, Shinji; Kuroki, Toshiro

    European journal of clinical microbiology & infectious diseases, 05/2024, Letnik: 43, Številka: 5
    Journal Article

    Fourier-transform infrared (FTIR) spectroscopy using the IR Biotyper and core genome single nucleotide polymorphism (cgSNP) analysis were performed on 12 Legionella isolates associated with an outbreak at a spa house in Kanagawa Prefecture, Japan, and 3 non-outbreak isolates. The discriminative power of FTIR spectroscopy for 48-h incubation conditions of L . pneumophila in this outbreak was lower than cgSNP-based typing but higher than serogroup typing. FTIR spectroscopy could screen outbreak isolates from a group of genetically related isolates and may be useful as an initial typing method in Legionella outbreak investigations.