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  • A self-immobilizing near-in...
    Li, Yuyao; Song, Heng; Xue, Chenghong; Fang, Zhijun; Xiong, Liqin; Xie, Hexin

    Chemical science (Cambridge), 06/2020, Letnik: 11, Številka: 23
    Journal Article

    Reported herein is a self-immobilizing near-infrared fluorogenic probe that can be used to image extracellular enzyme activity . Using a fluorophore as a quinone methide precursor, this probe covalently anchors at sites of activation and greatly enhances the fluorescence intensity at 710 nm upon enzymatic stimulus, significantly boosting detection sensitivity in a highly dynamic system.