Addiction is a relation of dependence, more or less alienating for an individual and more or less tolerated, sometimes even totally rejected by the individual's social environment, on a certain product, a certain practice or a situation. In young people addiction represents a search for sensations and a remedy for certain depression and/or anxiety symptoms. The pathology of addiction is first and foremost a pathology of sensations. The incriminated products are: tobacco and cannabis; alcohol and energy drinks associated with alcohol; new psychoactive substances (of the type of ethnobotanicals); drugs (withdrawal substances); real drugs (heroin, ecstasy); polydrug use (is quite frequent and currently includes alcohol+tobacco+ethnobotanicals+/- cannabis;). Doctors should not approach these patients alone, but together with the parents, school psychologists, school teachers, and Emergency medicine should evaluate the diagnostic modalities in intoxications with substances of abuse and psychoactive substances by taking into account: the young age of users, polyuse, repeated uses, excessive behaviours (e.g. induced alcoholic comas).