The subject of this research is the current state of cooperation between entrepreneurial and scientific sector in the Autonomous Province of Vojvodina, Republic of Serbia, estimated by owner/entrepreneur or manager of enterprises. The aim of the research is to determine relations and level of cooperation between business organizations (entrepreneurs) and universities (science). This is especially interesting since these relations between the entrepreneurial and scientific sectors have the great importance for the development of innovation in contemporary economies. The level of cooperation between the two above-mentioned sectors determines the innovative capacity of whole economy and possibilities of technology transfer. The level of cooperation with universities was explored in the sample of 200 small business organizations from the Autonomous Province of Vojvodina. Statistical methods used in the research are descriptive statistics and the Spearman's rho correlation. The results indicate a positive estimation of entrepreneurs regarding the cooperation with universities in the observed sample.