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  • Early Recurrence of Pancrea...
    FUJINAGA, Atsuro; HIRASHITA, Teijiro; ENDO, Yuichi; MASUDA, Takashi; OHTA, Masayuki; INOMATA, Masafumi

    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2021, 2021-00-00, Letnik: 82, Številka: 12
    Journal Article

    A 65-year-old woman underwent laparoscopic right nephrectomy for renal cell carcinoma (RCC). Nine years after the operation, abdominal computed tomography (CT) showed a 10-mm tumor in the pancreatic body, which was diagnosed as pancreatic metastasis of RCC. Considering that it was a single metastasis, laparoscopic enucleation of the pancreatic metastasis was performed, and the pathological diagnosis was pancreatic metastasis of RCC. The patient's postoperative course was uneventful, and she was discharged from the hospital 9 days after the operation. Six months after the pancreatectomy, abdominal CT showed two tumors in the pancreatic body, and the patient was diagnosed with recurrent pancreatic metastases. Considering multiple recurrence in the early postoperative period, a molecular-targeted drug was administered ; however, the drug was discontinued after 3 months due to side effects. Twelve months after the discontinuation of the drug, no new tumor appeared. However, laparoscopic distal pancreatectomy was performed because the old tumors increased in size. No recurrence was observed 1 year after the second pancreatectomy. In pancreatic metastasis of RCC, it is necessary to have a treatment strategy aiming at both preservation of function and long-term survival, keeping in mind the possibility of potential metastatic lesions.