High-frequency sequences composed of mixed siliciclastic-carbonate deposits may exhibit either vertical or horizontal changes between siliciclastics and carbonates. Vertical facies shifts occur between systems tracts and define a ‘reciprocal sedimentation’ pattern, typically consisting of transgressive/highstand carbonates and forced regressive/lowstand siliciclastics, although variations from this rule are common. Mixed systems with lateral facies change, usually typifying transgressive and/or highstand systems tracts, may exhibit proximal siliciclastics and distal carbonates or vice-versa, although variations may also occur along depositional strike. The marked variability of mixed siliciclastic-carbonate sequences makes the definition of a universal sequence stratigraphic model impossible, as the composition and geometries of systems tracts may change considerably, and sequence stratigraphic surfaces and facies contacts may vary in terms of occurrence and physical expression. However, some resemblance exists between siliciclastic sequences and mixed sequences showing lateral facies changes between siliciclastics and carbonates. In particular, these mixed sequences display 1) a stratal architecture of the clastic part of the systems tracts that is comparable to that of siliciclastic deposits, 2) a dominant role of the inherited physiography and of erosional processes, rather than carbonate production, in shaping the shelf profile, and 3) a local lateral juxtaposition of siliciclastic sandstones and carbonate bioconstructions due to hydrodynamic processes. These observations are helpful in predicting the location of porous and potential sealing bodies and baffles to fluid flow at the intra-high-frequency sequence scale, and ultimately they are useful for both petroleum exploration and production. •A sequence stratigraphic model for mixed siliciclastic-carbonate sequences is elaborated.•Vertical and horizontal switches between siliciclastic and carbonate deposits are illustrated.•This work helps to better understand the partitioning of porous bodies within sequences.