Objective: We provide a review and analysis of much of the published literature on visual perception issues that impact the design and use of head-mounted displays (HMDs). Background: Unlike the previous literature on HMDs, this review draws heavily from the basic vision literature in order to help provide insight for future design solutions for HMDs. Method: Included in this review are articles and books found cited in other works as well as articles and books obtained from an Internet search. Results: Issues discussed include the effect of brightness and contrast on depth of field, dark focus, dark ergence, and perceptual constancy; the effect of accommodation-vergence synergy on perceptual constancy, eyestrain, and discomfort; the relationship of field of view to the functioning of different visual pathways and the types of visual motor tasks mediated by them; the relationship of binocular input to visual suppression; and the importance of head movements, head tracking, and display update lag. Conclusion: This paper offers a set of recommendations for the design and use of HMDs. Application: Consideration of the basic vision literature will provide insight for future design solutions for HMDs.