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  • Ceftriaxone-Resistant Salmo...
    Fey, Paul D; Safranek, Thomas J; Rupp, Mark E; Dunne, Eileen F; Ribot, Efrain; Iwen, Peter C; Bradford, Patricia A; Angulo, Frederick J; Hinrichs, Steven H

    The New England journal of medicine, 04/2000, Letnik: 342, Številka: 17
    Journal Article

    Of the estimated 1.4 million salmonella infections that occur each year in the United States, most are in children and the elderly and approximately 600 are fatal. 1 Septicemia complicates at least 7 percent of the 40,000 culture-confirmed infections that are reported each year. 1 , 2 Although antibiotics are not essential for the treatment of most cases of salmonellosis, they can be lifesaving in persons with invasive disease. Expanded-spectrum cephalosporins (e.g., ceftriaxone) are commonly used to treat salmonella infections in children because of their pharmacodynamic properties and the very low prevalence of resistance to these agents. Since 1991, salmonella species that are . . .