We investigate the transfer properties of energy and helicity fluctuations in fully developed homogeneous and isotropic turbulence by changing the nature of the nonlinear Navier–Stokes terms. We perform a surgery of all possible interactions, by keeping only those triads that have sign-definite helicity content. In order to do this, we apply an exact decomposition of the velocity field in a helical Fourier basis, as first proposed by Constantin & Majda (Commun. Math. Phys, vol. 115, 1988, p. 435) and exploited in great detail by Waleffe (Phys. Fluids A, vol. 4, 1992, p. 350), and we evolve the Navier–Stokes dynamics keeping only those velocity components carrying a well-defined (positive or negative) helicity. The resulting dynamics preserves translational and rotational symmetries but not mirror invariance. We give clear evidence that this three-dimensional homogeneous and isotropic chiral turbulence is characterized by a stationary inverse energy cascade with a spectrum ${E}_{back} (k)\sim {k}^{- 5/ 3} $ and by a direct helicity cascade with a spectrum ${E}_{forw} (k)\sim {k}^{- 7/ 3} $ . Our results are important to highlight the dynamics and statistics of those subsets of all possible Navier–Stokes interactions responsible for reversal events in the energy-flux properties, and demonstrate that the presence of an inverse energy cascade is not necessarily connected to a two-dimensionalization of the flow. We further comment on the possible relevance of such findings to flows of geophysical interest under rotations and in thin layers. Finally we propose other innovative numerical experiments that can be achieved by using a similar decimation of degrees of freedom.