E-viri
Recenzirano
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Berchtold, Sonja; Grünwald, Barbara; Krüger, Achim; Reithmeier, Anja; Hähl, Teresa; Cheng, Tao; Feuchtinger, Annette; Born, Diana; Erkan, Mert; Kleeff, Jörg; Esposito, Irene
Cancer letters, 01/2015, Letnik: 356, Številka: 2Journal Article
Highlights • Col V is aberrantly overexpressed during progression of PDAC and often co-localized with its receptor β1-integrin. • Col V affects viability, adhesion, migration, and metastatic potential of pancreatic cancer cells. • The β1-integrin/FAK signaling pathway is identified as important mediator of Col V effects on tumor cells· • Col V and its downstream pathway represent possible therapeutic targets in PDAC.
