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Chen, Wansong; Huang, Qiyu; Ou, Weizhu; Hao, Yuanqiang; Wang, Liqiang; Zeng, Ke; Guo, Hongyan; Li, Juan; Liu, You-Nian
Small (Weinheim an der Bergstrasse, Germany), 04/2014, Letnik: 10, Številka: 7Journal Article
A new liposomal carrier embedded with a ratiometric fluorescent probe PNO is prepared. The integrated liposomes (PNO‐LIPs) exhibit blue fluorescence in serum. Triggered by the thiols exogenously or endogenously, PNO‐LIPs collapse with a burst drug release and a concurrent fluorescence change from blue to green. Furthermore, DOX‐loaded PNO‐LIPs improve the intracellular drug bioavailability.
